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Cellular Peptide Blend

BPC-157/TB-500 (Wolverine)

A synergistic peptide combination designed to support tissue repair and regenerative processes through complementary cellular mechanisms in animal research models. Premium Research Peptide.

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Compound Information

Technical specifications

BPC-157 PROFILE

Body Protection Compound-157

Type:

Synthetic pentadecapeptide

CAS Number:

137525-51-0

Molecular Weight:

1,419.5 g/mol

Acids:

15

Sequence:

GEPPPGKPADDAGLV

Origin:

Human gastric juice

TB-500 PROFILE

Thymosin Beta-4 (fragment)

Type:

Synthetic/endogenous peptide

CAS Number:

77591-33-4

Molecular Weight:

4,963 Da

Acids:

43

Active Region:

17LKKTET22 (actin binding)

Origin:

Thymus, platelets

BLEND INFORMATION

Why “Wolverine Stack”?

Nickname origin:

Enhanced healing properties

BPC-157 mechanism:

VEGFR2/Angiogenesis

TB-500 mechanism:

Actin/Cell migration

Common overlap:

Anti-inflammatory

Sources & References

Peer-reviewed research

GLOBALRPH CLINICAL REVIEW

BPC-157 and TB-500: Background, Indications, Efficacy, and Safety

2025
McAuley D

HSS JOURNAL (NIH/PUBMED CENTRAL)

Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review

2025 · DOI: 10.1177/155… · PMID: 40756949
Vasireddi N, Hahamyan H, Salata MJ,…

EXPERT OPINION ON BIOLOGICAL THERAPY

Thymosin β4: a multi-functional regenerative peptide. Basic properties and clinical applications

2012 · DOI: 10.1517/14712… · PMID: 22074294
Goldstein AL, Hannappel E, Sosne G,…

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES

A randomized, placebo-controlled, single and multiple dose study of intravenous thymosin beta4 in...

2010 · DOI: 10.1111/j.1749… · PMID: 20536472
Ruff D, Crockford D, Girardi G, Zhang Y

JOURNAL OF INVESTIGATIVE DERMATOLOGY

Thymosin beta4 accelerates wound healing

1999 · DOI: 10.1046/j.152… · PMID: 10469335
Malinda KM, Sidhu GS, Mani H,…

JOURNAL OF APPLIED PHYSIOLOGY

The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth...

2011 · DOI: 10.1152/jappl… · PMID: 21030672
Chang CH, Tsai WC, Lin MS, Hsu YH,…

SCIENTIFIC REPORTS (NATURE)

Modulatory effects of BPC 157 on vasomotor tone and the Src-Cav-1-eNOS signaling pathway in rats

2020 · DOI: 10.1038/s41… · PMID: 33046803
Hsieh MJ, Lee CH, Chueh HY, et al.

REGULATORY TOXICOLOGY AND PHARMACOLOGY

Preclinical safety evaluation of body protective compound-157, a potential drug for treating various wounds

2020 · DOI: 10.1016/j.yrt… · PMID: 32334036
Xu C, Sun L, Ren F, et al.

NATURE

Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac...

2004 · DOI: 10.1038/nat… · PMID: 15565145
Bock-Marquette I, Saxena A, White M…

GROWTH HORMONE & IGF RESEARCH

BPC-157 enhances growth hormone receptor expression in injured tendon tissue

2018 · DOI: 10.1016/j.ghir.2018.02.001
Staresinic M, Sebecic B, et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (PMC)

Progress on the Function and Application of Thymosin β4

2021 · DOI: 10.3390/ijms222413136
Xing Y, et al.

CLINICALTRIALS.GOV

PCO-02 - Safety and Pharmacokinetics Trial (Phase 1)

2015

COMBINED LITERATURE (META)

COMBINED LITERATURE (META)

2025

Not for human consumption. This product is sold exclusively for research and educational purposes. It is not intended to diagnose, treat, cure, or prevent any disease.

All clinical trial data and research findings presented on this page are sourced from peer-reviewed journals and official publications. They are provided for educational reference only and should not be interpreted as medical advice or product claims.

By purchasing this product, you confirm that you are a qualified researcher and will use it in accordance with all applicable laws and regulations.

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