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Circadian Peptide

DSIP

A 9-acid peptide that modulates delta-wave sleep architecture and circadian rhythm signaling, studied for sleep onset mechanisms in research models. Premium Research Peptide.

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$29.99
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Compound Information

Technical specifications

MOLECULAR PROFILE

What Is DSIP?

Naturally occurring nonapeptide first isolated from rabbit brain in 1977

Type:

Synthetic nonapeptide

CAS Number:

62568-57-4

Molecular Formula:

C35H48N10O15

Molecular Weight:

848.8 g/mol

Acids:

9 residues

Sequence:

Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu

STORAGE REQUIREMENTS

Stability Information

Handle with care to maintain potency

Lyophilized (powder)

-20°C · protect from light

Reconstituted

2-8°C · use within 24 hours

Stability

15 minutes (plasma half-life)

RESEARCH STATUS

Development History

First isolated from rabbit brain in 1977 by Schoenenberger & Monnier

Discovery:

1977, Switzerland

Discoverers:

Schoenenberger & Monnier

Origin:

Rabbit mesodiencephalic ventricle

INN Name:

Emideltide

Human Studies:

1980s-present

Regulatory Status:

Research compound

Sources & References

Peer-reviewed research

EUROPEAN JOURNAL OF ANAESTHESIOLOGY

Delta sleep-inducing peptide

2001
Pollard BJ, Pomfrett CJD

INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY, THERAPY, AND TOXICOLOGY

Acute and delayed effects of DSIP on human sleep behavior

1981 · PMID: 6895513
Schneider-Helmert D, et al.

NEUROPSYCHOBIOLOGY

Effects of delta sleep-inducing peptide on sleep of chronic insomniac patients

1992 · DOI: 10.1159/00… · PMID: 1299794
Bes F, Hofman W, Schuur J, Van Boxte…

EUROPEAN NEUROLOGY

DSIP in the treatment of withdrawal syndromes from alcohol and opiates

1984 · DOI: 10.1159/00… · PMID: 6548969
Dick P, Costa C, Fayolle K, et al.

EUROPEAN NEUROLOGY

Therapeutic effects of delta-sleep-inducing peptide (DSIP) in patients with chronic, pronounced pain...

1984 · DOI: 10.1159/00… · PMID: 6548970
Larbig W, Gerber WD, Kluck M,…

NEUROPSYCHOBIOLOGY

Effects of DSIP in man: Multifunctional psychophysiological properties besides induction of...

1983 · PMID: 6689058
Schneider-Helmert D,…

INTERNATIONAL JOURNAL OF NEUROSCIENCE

DSIP—a tool for investigating the sleep onset mechanism: a review

1988 · DOI: 10.3109/0020… · PMID: 3286557
Yehuda S, Carasso RL

MOLECULES

Delta Sleep-Inducing Peptide Recovers Motor Function in SD Rats after Focal Stroke

2021 · DOI: 10.3390/mo… · PMID: 34500605
Tukhovskaya EA, et al.

PUBCHEM DATABASE

Delta Sleep-Inducing Peptide

Not for human consumption. This product is sold exclusively for research and educational purposes. It is not intended to diagnose, treat, cure, or prevent any disease.

All clinical trial data and research findings presented on this page are sourced from peer-reviewed journals and official publications. They are provided for educational reference only and should not be interpreted as medical advice or product claims.

By purchasing this product, you confirm that you are a qualified researcher and will use it in accordance with all applicable laws and regulations.

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