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Cellular Peptide

KPV

A 3-acid tripeptide (Lys-Pro-Val) derived from the C-terminus of alpha-melanocyte-stimulating hormone that inhibits NF-κB activation via PepT1-mediated cellular uptake in preclinical inflammatory research models. Premium Research Peptide.

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$39.99
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Certificate of Analysis

Third Party Tested by Freedom Diagnostics

99.49%

PURITY

Variant:

KPV 10mg

Lot #:

KP1120

Labeled:

10mg

Actual:

13.76mg

Tested:

Feb 4, 2026

Compound Information

Technical specifications

MOLECULAR PROFILE

What Is KPV?

Type:

Synthetic tripeptide

Sequence:

Lys-Pro-Val (KPV)

acids:

3

Molecular formula:

C16H30N4O4

Molecular weight:

342.43 g/mol

CAS Number:

67727-97-3

Origin:

α-MSH residues 11-13

PARENT COMPOUND

Relationship to α-MSH

Parent peptide:

α-Melanocyte-Stimulating Hormone

α-MSH length:

13 amino acids

KPV position:

C-terminal (11-13)

Activity retained:

Anti-inflammatory effects

MCR binding:

NOT required for activity

STORAGE REQUIREMENTS

Stability Information

Lyophilized (powder)

-20°C · long-term

Reconstituted

2-8°C · use within 7 days

Reconstituted

Store away from light

Sources & References

Peer-reviewed research

GASTROENTEROLOGY

PepT1-Mediated Tripeptide KPV Uptake Reduces Intestinal Inflammation

2008 · DOI: 10.1053/j.gas… · PMID: 18061177
Dalmasso G, Charrier-Hisamuddin L,…

BRITISH JOURNAL OF PHARMACOLOGY

α-MSH Related Peptides: A New Class of Anti-Inflammatory and Immunomodulating Drugs

2000 · DOI: 10.1111/j.1476-5381.2000.0…
Luger TA, Brzoska T, Scholzen TE, et al.

MOLECULAR PHARMACEUTICS

Orally Targeted Delivery of Tripeptide KPV via Hyaluronic Acid-Functionalized Nanoparticles...

2017 · PMID: 28548842
Xiao B, Xu Z, Viennois E, et al.

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES

Melanocortin-Derived Tripeptide KPV Has Anti-Inflammatory Potential in Murine Models of Inflammatory...

2008 · PMID: 18226903
Kannengiesser K, Maaser C,…

2008 · PMID: 18226903 Kannengiesser K, Maaser C,...

Alpha-Melanocyte-Stimulating Hormone and Related Tripeptides: Biochemistry, Antiinflammatory and...

1999
Brzoska T, Luger TA, Maaser C, et al.

Not for human consumption. This product is sold exclusively for research and educational purposes. It is not intended to diagnose, treat, cure, or prevent any disease.

All clinical trial data and research findings presented on this page are sourced from peer-reviewed journals and official publications. They are provided for educational reference only and should not be interpreted as medical advice or product claims.

By purchasing this product, you confirm that you are a qualified researcher and will use it in accordance with all applicable laws and regulations.

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